Could stress be a secret to hair growth?

This could be the case, according to a new study by the Department of Stem Cell and Regeneration Biology at Harvard University led by Seku Choi.

In general, a person’s hair growth cycle has three stages – growth, breakage, and rest. In the first stage, the hair is a continuous rod, but the hair stops growing and the lower part is reduced during the second part. In the third stage, the hair eventually falls out.

Although the general link between hair loss and chronic stress has been known for some time to be linked to hair loss, the exact mechanism behind this link remains a mystery.

Known hair follicle cells (HFSCs) play an important role in hair growth by interpreting internal and external signals. With this in mind, Cho and other researchers have tested the role of another part of the body: the stress-hormone-adrenal gland plays a role in the cycle. To do this, they were surgically removed from the rats.

Without adrenal glands to produce stress hormones, the “rest” rate of rats in their hair cycles was very short, three times more than normal. However, hair growth is suppressed when they eat the stress hormone corticosteroid, which is produced by the adrenal glands of animals.

So does cortisone play a role in hair loss? This is what it means. HFSs recognize the stress hormone through symptoms, and not by identifying the hormone itself. It was determined that the researchers selected a protein known as a glucocorticoid receptor (dermal papillae). These receptors are the way the hormone signals HFSs.

But how do skin papillae transmit the signal? According to the study, this is done by another protein, growth factor-dependent 6 (GAS6). With this protein, the signal is transmitted to the HCCC via another protein, the XL receptor.

These findings were published in an educational journal Nature, Map out how stress affects hair loss, and pave the way for treatment of stress-induced hair loss.
In addition, the findings also follow the outbreak of the COVID-19 pandemic, which caused great concern to the world’s population during the war on the disease.
However, the study warns that many more issues need to be addressed. For example, corticosteroid is not a human stress hormone, but is considered a wash with human cortisol. Therefore, it is not known whether the process is exactly the same. Second, hair cycle stages have different intervals between people, so it is not clear whether hormones affect them in the same way. Third, GAS6 protein is not limited to this specific marker. In fact, the researchers involved a number of different genes involved in HFSs. As a result, disrupting it can have other unintended consequences. In particular, there is a risk that this ignorance could lead to the development of HFCs, which can lead to mutations.
It should also be noted that there are several types of hair loss associated with stress. According to the Mayo Clinic, one of these is telogen influenza, which leads to severe hair loss when hair is at rest. The other two are different.

One of these is the stress, frustration, and other negative emotions known as trichomoniasis.

The third form is very different. This condition, also known as alopecia areata, is a condition in which the body’s immune system attacks the hair follicles and causes hair loss. There are many possible causes for this condition, and stress is one of them – although the condition itself is known to be a major cause of psychological stress.

However, the findings of the study found important links between stress and hair loss, and this may pave the way for future studies to further explore these links.